URIC ACID LEVELS BY GENDER IN THE COMMUNITY
DOI:
https://doi.org/10.37771/kjn.v8i1.1491Keywords:
Community-Based Study, Ages, Cross-Sectional Study, Blood Glucose, Hyperuricemia, Cholesterol, Sex Differences, Uric Acid, Uric Acid LevelsAbstract
Uric acid is a metabolic health condition with a rising global prevalence and the potential to cause complications such as gout, arthritis, kidney disorders, and cardiovascular diseases. Sex is recognized as a key biological determinant influencing uric acid levels; however, community-based evidence in North Sulawesi remains limited. This study aimed to analyze and compare uric acid levels based on sex among community residents. A descriptive correlational study with a cross-sectional design was conducted among 226 respondents aged 40–50 years, selected purposively in Sarongsong 2 Village. Uric acid levels were measured using the Easy Touch 3-in-1 device after fasting. Descriptive statistics were used for univariate analysis, while differences between groups were assessed using the Mann–Whitney U test. The findings revealed that most male participants were hyperuricemic (51%), whereas most females were normouricemic (67.74%). The mean uric acid level in males (x̄ = 8.258; SD = 10.13975) was higher than in females (x̄ = 7.0460; SD = 10.05560). Statistical analysis showed a significant difference in uric acid levels between sexes (p < 0.001). In conclusion, uric acid levels differ significantly by sex, with males exhibiting higher levels than females. These findings highlight the importance of sex-specific approaches in community-based prevention strategies. Future research should incorporate lifestyle-related risk factors and include postmenopausal women to better capture hormonal influences across the lifespan.
Asam urat merupakan salah satu masalah kesehatan metabolik yang prevalensinya terus meningkat dan berpotensi menimbulkan komplikasi seperti gout arthritis, gangguan ginjal, serta penyakit kardiovaskular. Jenis kelamin diketahui sebagai faktor biologis yang memengaruhi kadar asam urat, namun data berbasis komunitas di Sulawesi Utara masih terbatas. Penelitian ini bertujuan untuk menganalisis dan membandingkan nilai kadar asam urat berdasarkan jenis kelamin pada masyarakat Kelurahan Sarongsong 2. Penelitian ini menggunakan desain descriptive correlation dengan pendekatan cross-sectional. Sampel berjumlah 226 responden usia 40–50 tahun yang dipilih melalui purposive sampling. Pengukuran kadar asam urat dilakukan menggunakan alat Easy Touch 3-in-1 setelah responden berpuasa. Analisis univariat menggunakan frekuensi, persentase, mean, dan standar deviasi. Analisis bivariat dilakukan menggunakan Mann-Whitney U test. Hasil menunjukkan sebagian besar laki-laki berada pada kategori hiperurisemia (51%), sedangkan perempuan mayoritas berada pada kategori normourisemia (67,74%). Rerata kadar asam urat laki-laki (x=8.258; SD=10.13975) lebih tinggi dibandingkan perempuan (x=7.0460; SD=10.05560). Uji Mann-Whitney menunjukkan terdapat perbedaan yang signifikan antara kadar asam urat berdasarkan jenis kelamin (p=0,000). Berdasarkan hasil, dapat disimpulkan bahwa terdapat perbedaan signifikan kadar asam urat antara laki-laki dan perempuan, di mana laki-laki cenderung memiliki kadar lebih tinggi. Direkomendasikan pada penelitian selanjutnya untuk mengkaji faktor risiko gaya hidup dan memasukkan perempuan menopause untuk analisis yang lebih komprehensif.
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